Tricia R. Serio, Ph.D.

Title
Professor and Department Head
Department
Department of Molecular and Cellular Biology
Institution
University of Arizona
Address
LSS 444
State
RI
E-mail
tserio[at]email.arizona.edu
Website
https://vivo.brown.edu/display/tseriop
Research Field
Molecular Biology
Award Year
2003

Research

In a variety of systems, proteins have been linked to processes historically limited to nucleic acids, such as infectivity and inheritance. Such proteins, termed prions, adopt multiple physical and therefore functional states in vivo, an attribute underlying their atypical roles in the cell. Our work seeks to elucidate the molecular mechanisms that module prion protein conformational flexibility in vivo using the yeast Saccharomyces cerevisiae as an experimental model.

Scholar Keywords