Fernando D. Camargo, Ph.D.

Title
Associate Professor
Department
Stem Cell Program
Institution
Boston Children's Hospital, Harvard University
Address
One Blackfan Circle
Karp Building #9-211
City, State, Zip
Boston, MA 2115
Phone
(617) 919-2102
E-mail
fernando.camargo[at]tch.harvard.edu
Website
http://www.hsci.harvard.edu/people/fernando-camargo-phd
Research Field
Developmental Biology
Award Year
2010

Research

My lab studies how tumor growth is inhibited in a tissue-wide context. Our hypothesis is that the same intrinsic mechanisms that regulate organs to reach an appropriate size in their own environment may normally act as tumor suppressors. Using a mouse model, we are determining whether mechanisms controlling tissue size act as critical regulators of tumor growth and have focused our studies on the Hippo pathway of genes to test this model. Using a range of molecular biological techniques and RNA interference (RNAi) screens we hope to identify novel regulators of a signaling pathway, known as the Hippo pathway, and to then determine their role as tumor suppressor genes.