Thomas J. O'Dell, Ph.D.

Title
Professor
Department
Department of Physiology
Institution
University of California, Los Angeles
Address
Gonda Neuroscience and Genetics Research Center
695 Charles Young Drive South
City, State, Zip
Los Angeles, CA 90095
Phone
(310) 206-4654
E-mail
todell[at]mednet.ucla.edu
Website
http://www.bri.ucla.edu/people/thomas-j-odell-phd
Research Field
Neuroscience
Award Year
1996

Research

Synaptic and molecular mechanisms in learning and memory formation. My lab is currently investigating the synaptic and molecular mechanisms involved in learning and memory formation in the mammalian central nervous system. Electrophysiological techniques are used to study synaptic transmission in a variety of in vitro preparations but most work concerns the mechanisms responsible for long-lasting changes in synaptic transmission that occur in the hippocampus, a region of the brain known to have an important role in learning and memory. In our experiments we use electrophysiological, pharmacological, and molecular genetic (transgenic mice) approaches to decipher the molecular components of the biochemical pathways responsible for memory formation in the mammalian brain and eventually hope to understand how alterations in these pathways may contribute to the memory impairment that occurs in pathological conditions such as Alzheimer’s disease or even as a result of normal aging.