James J. Chou, Ph.D.

Title
Professor
Department
Department of Biological Chemistry & Molecular Pharmacology
Institution
Harvard University
Address
250 Longwood Avenue, SGM 109
City, State, Zip
Boston, MA 2115
Phone
(617) 432-2920
E-mail
james_chou[at]hms.harvard.edu
Website
http://chou.med.harvard.edu/jameschou.htm
Research Field
Structural Biology
Award Year
2004

Research

The long-term interest of our research is in understanding the molecular mechanism of membrane-embedded proteins including ion channels, receptors, and transporters. The main biophysical tool we use to study these systems is solution NMR spectroscopy, although we use other high resolution techniques as appropriate for answering mechanistic questions. Our major challenge is to push the envelope of solution NMR to enable structure determination of alpha helical membrane proteins, not only by developing and testing new methods but also by applying them to address important questions in biology.