Arul M. Chinnaiyan, M.D., Ph.D.

Title
Investigator, Howard Hughes Medical Institute
Department
Department of Pathology
Institution
University of Michigan
Address
5316 CCGC
1500 E. Medical Center Drive
City, State, Zip
Ann Arbor, MI 48109
Phone
(734) 936-1887
E-mail
arul[at]umich.edu
Website
http://www.ccmb.med.umich.edu/node/204
Research Field
Genetics
Award Year
2002

Research

Dr. Chinnaiyan's laboratory is focused on using functional genomic, proteomic, metabolomic and bioinformatics approaches to dissect and understand cancer biology as well as discover biomarkers. He and his collaborators have characterized a number of biomarkers of prostate cancer including AMACR, EZH2, hespin and sarcosine. His laboratory identified recurrent gene fusions of TMPRSS2 to ETS family transcription factors in prostate cancer, potentially redefining the molecular basis of prostate cancer as well as other common epithelial cancers. His laboratory developed the popular cancer profiling bioinformatics resource called Oncomine (www.oncomine.org).