James L. Sherley, M.D., Ph.D.

Title
Director
Institution
Asymmetrex LLC
Address
P.O. Box 301179
City, State, Zip
Boston, MA 02130
Phone
(617) 990-6819
E-mail
jlsherley[at]gmail.com
Website
https://sites.google.com/site/adultstemcelltechnologycenter/
Research Field
Molecular Biology
Award Year
1993

Research

Our laboratory pursues normal molecular and biochemical processes in adult stem cells that are involved in cancer initiation and that contribute to aging. Adult stem cells are rare tissue cells that continuously replace expired tissue cells. Investigations of their specialized properties will yield new therapies for injured, diseased, and aging tissue cells. We employ an integrated approach, incorporating both basic and applied research strategies, to elucidate novel mechanisms of adult stem cell-specific functions and apply the knowledge to improve methods for identifying adult stem cells and producing them in large number for therapeutic development.