- Postdoctoral Fellow
- Department of Biochemistry and Molecular Biophysics
- Columbia University
650 West 168th Street
Black Building Room 536
- City, State, ZIP
- New York, NY 10032
- United States
- (212) 342-2943
- [email protected]
- Research field
- Award year
- Country of origin
- Mentor name
- Eric C. Greene, Ph.D.
The Greene lab investigates how a cell’s DNA repair machinery corrects errors made during DNA replication. When cells copy their chromosomes, replication machinery occasionally makes mistakes. Most of these errors are fixed by a system that removes the faulty nucleotide and replaces it with the correct one, but if missed by the repair machinery the errors can cause diseases such as cancer. Combining biochemical, molecular biology and cell biological methods with a state-of-the-art microscopic technique developed in Dr. Greene’s lab, I will track the movement of repair proteins to see whether they follow on the heels of the replication machinery and whether the replication halts while mistakes are corrected. These findings could provide insights into the biology of cancers that are associated with a failure of this corrective system.
2014 Search Pew Fellows
- Matias A. Alvarez-Saavedra, Ph.D.
- Ezequiel M. Arneodo, Ph.D.
- Andrea M. Caricilli, Ph.D.
- Luisina De Tullio, Ph.D.
- Armando Hernandez Garcia, Ph.D.
- Pablo A. Lara-Gonzalez, Ph.D.
- Juan David Ramirez Gonzalez, Ph.D.
- Daniela Paula T. Thomazella, Ph.D.
- Alejandro Vasquez Rifo, Ph.D.
- Yuriria Vázquez Zúñiga, Ph.D.