The aim of Nanobiomaterial lab at National Univ of La Plata is focus on the development of molecular controlled release scaffolds based on biopolymers. Natural and/or modified biopolymers were used to develop films and micro- and nano-spheres containing molecules of interest (e.g. anticancer drugs, antiobiotics, enzymes). Spectroscopy and microscopy analysis were used to determine interaction between matrix components and with the environment. “Smart” (temperature and/or pH) sensitive gels containing superparamagetic nanoparticles were used to deliver the drug to appropriate targets are under study.