Holger Sondermann, Ph.D.

- Title
- Associate Professor
- Department
- Molecular Medicine
- Institution
- Cornell University
- Address
- College of Veterinary Medicine
- City, State, ZIP
- Ithaca, NY 14853
- Phone
- (607) 253-3318
- [email protected]
- Website
- http://sondermannlab.vet.cornell.edu/
- Research field
- Microbiology
- Award year
- 2008
Research
My lab is interested in deciphering the basic regulatory principles in signal transduction networks on a molecular level, focusing on growth factor receptor signaling. In particular, we study the role of scaffolding proteins and other regulators signal transduction in this pathway, using a combination of X-ray crystallography, biophysical and cellular approaches. Scaffolds, which serve as docking hubs for the signaling switches, provide specificity and higher-order control in signaling reactions. Understanding the architecture, mode of action and regulation of these processes will elucidate how cells respond to various inputs producing distinct outputs by using a limited set of molecules.
Scholar Keywords
2008 Search Pew Scholars
- Gilad Barnea, Ph.D.
- Laurie A. Boyer, Ph.D.
- Antonio J. Giraldez, Ph.D.
- Aaron D. Gitler, Ph.D.
- Felicia D. Goodrum, Ph.D.
- Richard I. Gregory, Ph.D.
- Jianping Jin, Ph.D.
- Anatol C. Kreitzer, Ph.D.
- Deborah J. Lenschow, M.D., Ph.D.
- Ian J. MacRae, Ph.D.
- Bryce E. Nickels, Ph.D.
- Susannah Rankin, Ph.D.
- John Rawls, Ph.D.
- Seth M. Rubin, Ph.D.
- Holger Sondermann, Ph.D.
- Michael A. Sutton, Ph.D.
- Benjamin R. tenOever, Ph.D.
- Leor S. Weinberger, Ph.D.
- Julia Zeitlinger, Ph.D.
- Hui Zong, Ph.D.