Adrienne A. Rogalski-Wilk, Ph.D.
![Adrienne Rogalski Wilk](/-/media/legacy/legacy-and-pre-launch-image-edits/scholars/1987/adrienne-rogalski-wilk.jpg?la=en&h=90&w=75&hash=53AF0594F41FBC39955CAE2E93CF9A15)
- Title
- Associate Professor
- Department
- Department of Anatomy and Cell Biology
- Institution
- University of Illinois at Chicago
- Address
-
Room 680 CME
808 S. Wood Street - City, State, ZIP
- Chicago, IL 60680
- Phone
- (312) 996-0130
- [email protected]
- Website
- http://www.uic.edu/depts/mcan/aarw.htm
- Research field
- Cell Biology
- Award year
- 1987
Research
Our laboratory has had a long standing interest in understanding the molecular basis of how actin microfilaments bind to cell membranes. We are presently focused on discovering how actin filaments assume specific associations with the plasma membrane at cell cortex domains other than the leading edge. An important cortical actin domain of this type involves caveolae-rich plasma membrane regions restricted to the lateral edge domains of motile cells. In interphase cells, these lateral edge actin-rich, membrane cortex regions are active in cell processes of endocytosis- clathrin and nonclathrin-coated mediated, cell surface recycling and signal transduction. Here caveolae are either aligned with or intercalated between prominent, lateral-oriented actin bundles, but the underlying molecular nature of these interactions are unclear. We have hypothesized that at caveolae-rich plasma membrane regions there are unique membrane-actin associations.
Scholar Keywords
1987 Search Pew Scholars
- Robert E. Boswell, Ph.D.
- Roger Brent, Ph.D.
- Shing Y. Chiu, Ph.D.
- Tucker Collins, M.D., Ph.D.
- Sandra J.F. Degen, Ph.D.
- Diane O. Etchison, Ph.D.
- Katherine A. Jones, Ph.D.
- Lawrence C. Kuo, Ph.D.
- Jeffrey L. Noebels, M.D., Ph.D.
- Marilyn C. Pike, M.D., Ph.D.
- Marilyn D. Resh, Ph.D.
- Adrienne A. Rogalski-Wilk, Ph.D.
- Philip M. Rosoff, M.D.
- Christopher A. Ross, M.D., Ph.D.
- Nilabh Shastri, Ph.D.
- Michael P. Snyder, Ph.D.
- Alison A. Weiss, Ph.D.
- Morris F. White, Ph.D.
- Alexander S. Whitehead, D. Phil.