Michael S. Kuhns, Ph.D.

Pew.Feature.Scholar.Bio.Title
Assistant Professor
Pew.Feature.Scholar.Bio.Department
Department of Immunobiology
Pew.Feature.Scholar.Bio.Institution
University of Arizona
Pew.Feature.Scholar.Bio.Address
1656 E Mabel Street
P.O. Box 245221
Pew.Feature.Scholar.Bio.City, Pew.Feature.Scholar.Bio.State, Pew.Feature.Scholar.Bio.Zip
Tucson, AZ 85724
Pew.Feature.Scholar.Bio.Phone
(520) 626-6461
Pew.Feature.Scholar.Bio.Email
[email protected]
Pew.Feature.Scholar.Bio.Website
http://immunobiology.arizona.edu/faculty/michael-s-kuhns-phd
Pew.Feature.Scholar.Bio.ResearchField
Immunology
Pew.Feature.Scholar.Bio.AwardYear
2011

Research

Effective immunity to pathogens requires that coordinated, multi-cellular responses emerge from a myriad of "conversations" that take place between cells of the innate and adaptive immune compartments. My lab is working to understand the molecular mechanism that mediate the conversations that occur between antigen-presenting cells and T cells that determine if and how a T cell responds to antigen. We are using a variety of classic molecular, cellular, and biochemical techniques, as well as more modern live cell imaging approaches, to probe these processes. We are also developing mouse model systems to determine how individual mechanisms contribute to T cell responses during pathogenic infection or autoimmunity. Altogether, our work is aimed at increasing our basic and practical understanding of T cell activation and regulation.

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