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Between 2016 and 2017, congenital syphilis rates rose 60 percent in the South and 41 percent in the West, compared with 6 percent climbs in both the Midwest and Northeast. States reporting the highest rates of congenital syphilis in 2017 were Louisiana, Nevada, California, Texas and Florida. Across the country, cases ranged from zero in states such as Wyoming and Maine up to 281 in California.

Source: U.S. Centers for Disease Control and Prevention, "Sexually Transmitted Disease Surveillance 2017"