The Southern New Hampshire Planning Commission (SNHPC) conducted a health impact assessment (HIA) that examined the potential health impacts of the Second Street Corridor Project in Manchester, New Hampshire. The Second Street Corridor Access and Mixed Use Overlay Zoning Project is funded by a grant provided to the City of Manchester through the New Hampshire Community Planning Grant Program from the New Hampshire Housing Finance Authority (NHHFA). The purpose of this project is to develop access management strategies and a mixed-use overlay zoning district for Second Street between the Manchester-Bedford town line and Granite Street at Exit 5 off I-293. The overall goal of the Second Street Corridor Project is to improve the use, mobility, and safety of the corridor for all modes of travel (pedestrian, bicycle, vehicle, transit) as well as to promote economic growth and infill development to revitalize and improve the corridor for all users. The HIA project also aims to create a model for multi-sector collaboration on specific projects that could influence health.