Jhimmy Talbot, Ph.D.

Title
Postdoctoral Fellow
Department
Skirball Institute of Biomolecular Medicine
Institution
New York University
Address
540 First Avenue
Skirball 2-14/17
City, State, Zip
New York, NY 10016
Country
United States
Phone
212-263-7520
E-mail
jhimmytal[at]yahoo.com.br
Website
http://www.med.nyu.edu/skirball-lab/littmanlab//Home.html
Research Field
Immunology
Award Year
2015
Country Of Origin
Brazil
Mentor Name
Dan R. Littman, M.D., Ph.D.

Research

In Dr. Littman's lab we are exploring the role of the enteric (gut) nervous system in intestinal immune function and its crosstalk with resident microbiota. It is known that the maintenance of a balanced, but poised intestinal immune system is heavily influenced by the interaction of intestinal microbiota and immune cells. Recent studies suggest that the nerve cells that control gut activity can recognize microbiota metabolites, but there is not yet a good understanding of how this recognition translates into modulation of intestinal immune homeostasis. Using sophisticated methods in cell and molecular biology, genetics and immunology, I will determine whether activation of intestinal neurons influences the action of immune cells in the gut-- and how resident microbes promote this interaction. This work could lead to the identification of new treatments for intestinal disorders such as chronic inflammatory bowel syndrome.