Erika C. Garay, Ph.D.

Title
Postdoctoral Fellow
Department
Department of Developmental & Molecular Biology
Institution
Albert Einstein College of Medicine
Address
1300 Morris Park Avenue
Chanin Building, Room 504
City, State, Zip
Bronx, NY 10461
Country
United States
Phone
718-430-2689
E-mail
egaray.gar[at]gmail.com
Website
http://www.einstein.yu.edu/faculty/8784/ana-maria-cuervo/
Research Field
Cell biology
Award Year
2015
Country Of Origin
Mexico
Mentor Name
Ana Maria Cuervo, M.D., Ph.D.

Research

The Cuervo lab studies the pathways that allow cells to remove damaged molecular material--an activity that is compromised as we age. Over time, our cells accumulate proteins that are incorrectly folded and subcellular structures that are no longer functional. To avoid becoming overwhelmed, mammalian cells have two systems for clearing this unwanted molecular debris. Although these systems can compensate for each other should one fail, both tend to malfunction during aging and in some age-related diseases such as Alzheimer's or Parkinson's disease. Now, I will identify the regulatory components that allow these systems to balance and augment one another-- findings that could lead to novel therapeutics that promote the clearance of the toxic cell debris that accumulates as we age and in diseases of aging.