Facundo G. Pelorosso, Ph.D.

Title
Resident
Department
Department of Pathology
Institution
University of Buenos Aires
Address
Araoz 2438
7mo 62
City, Zip
Buenos Aires, C1425DGJ
Country
Argentina
Phone
54-11-4831-64333
E-mail
facundo.pelorosso[at]gmail.com
Website
http://www.hospitaldeclinicas.uba.ar/
Research Field
Genetics
Award Year
2009
Country Of Origin
Argentina
Mentor Name
Allan Balmain, Ph.D., FRSE

Research

Gene expression networks from mouse skin have provided new insights into the genetic architecture of this tissue. However, the depth of these networks has not been completely explored as a tool for novel in vivo functional annotation of genes in specific signaling pathways and biological processes. My research exploits skin gene expression networks to identify metabolic pathways related to carbohydrate and lipid metabolism and transcriptional programs linked to adipogenesis and adipokine signaling. Our studies underscore the versatility and power of an easily available tissue, such as skin, for network modeling of systemic transcriptional programs involved in multiple pathways, including lipid metabolism and adipogenesis.