Guillermo Ariel Yudowski, Ph.D.

Title
Assistant Professor
Department
Department of Anatomy & Neurobiology
Institution
University of Puerto Rico
Address
201 Calle Norzagaray
City, State, Zip
San Juan, PR 901
Country
Puerto Rico
Phone
(787) 724-2148
E-mail
guillermo.yudowski[at]upr.edu;
Website
http://theylab.org/
Research Field
Neuroscience
Award Year
2003
Country Of Origin
Argentina
Mentor Name
Mark Von Zastrow, Ph.D.

Research

Our goal is to understand the molecular events by which mammalian neurons modulate their sensitivity to external stimuli. To address these issues, we developed a new approach combining live cell imaging and molecular biology to examine the trafficking and signaling of surface receptors in real-time. We have focused our work on two different types of receptors; the G-protein coupled receptors (GPCR), the largest family of receptors in the central nervous system and the AMPA-type glutamate receptor, mediator of most of the fast excitatory transmission in the central nervous system.
Our results present new information regarding the location; regulation and signaling of these receptors in real-time, providing unprecedented insight into neuronal function facilitating the search for more effective and specific therapies for complex CNS disorders.