Carolina Perez Castro, Ph.D.

Title
Group Leader and Adjunct Researcher
Department
Department of Physiology and Molecular and Cell Biology
Institution
University of Buenos Aires
Address
Godoy Cruz 2390, C1425FQA
City
Buenos Aires
Country
Argentina
E-mail
cperezcastro[at]ibioba-mpsp-conicet.gov.ar
Website
http://www.ibioba-conicet.gob.ar/index_i.php
Research Field
Bioinformatics; genetics
Award Year
2003
Country Of Origin
Argentina
Mentor Name
Rik Derynck, Ph.D.

Research

My group is currently working on the elucidation of the molecular mechanisms underlying ES cells and early differentiation. Our main goal is to understand how TGFbeta through Smad proteins regulates genes that are potentially critical for self-renewal property and cell behavior. The main experimental strategies in the lab include: Gene expression analysis and Bioinformatics. Stable gene transfer in cell culture systems and genome silencing with viral vectors. The understanding of how pluripotency and cell plasticity are regulated will have a large impact on developmental biology studies, pathologies and regenerative medicine.