David Padrón-Pérez, Ph.D.

Title
Associate Professor of Biology
Department
Department of Arts, Sciences, Humanities & Kinesiology
Institution
Navarro College
City, State, Zip
Corsicana, TX 75110
Country
United States
E-mail
david.padron-perez[at]navarrocollege.edu
Research Field
Cell biology
Award Year
2001
Country Of Origin
Mexico
Mentor Name
Michael G. Roth, Ph.D.

Research

During the formation of vesicles that occurs in membrane traffic, membrane lipids undergo dramatic structural rearrangements. Thus, the cell must, somehow, overcome the energy barrier of the required lipid structural changes. One way of reducing the energy barrier is to modify the membrane lipid composition, making such membranes conducive to vesicle formation. In fact, lipid-modifying enzymes such as phospholipase D and phosphatidylinositol phosphate kinase have been implicated in membrane traffic. My research investigates the role of such enzymes in regulating rates of membrane traffic, particularly the internalization of the epidermal growth factor receptor, and aims to elucidate the mechanistic basis of such regulation.