Niels Ringstad, Ph.D.

Title
Assistant Professor
Department
Skirball Institute of Biomolecular Medicine
Institution
New York University
Address
540 First Avenue
SK 5-14
City, State, Zip
New York, NY 10016
Phone
(212) 263-3753
E-mail
Niels.Ringstad[at]med.nyu.edu
Website
http://www.med.nyu.edu/skirball-lab/ringstadlab//
Research Field
Neuroscience
Award Year
2011

Research

Neuron-neuron communication is mediated by the regulated release of neurotransmitters. We are studying the molecular biology of chemical neurotransmission using genetic and physiological studies of the roundworm Caenorhabditis elegans, which has an anatomically simple nervous system that uses most of the major neurotransmitters found in the human brain. We have specific interests in two types of neurotransmitters: monoamines and neuropeptides. Monoamines, such as dopamine, play critical roles in brain function and are associated with a host of neurological and psychiatric disorders including Parkinson's disease, schizophrenia and major depression. Neuropeptides play diverse modulatory roles in the brain where they function in circuits that generate complex innate behaviors. We aim to understand molecular mechanisms by which monoamine and peptide neurotransmitters function in the nervous system in order to identify new therapeutic targets for the treatment of diseases associated with their dysfunction.