Craig H. Bassing, Ph.D.

Title
Associate Professor
Department
Department of Pathology
Institution
Children's Hospital of Philadelphia, University of Pennsylvania
Address
4054 Colket Translational Research Building
3501 Civic Center Boulevard
City, State, Zip
Philadelphia, PA 19104-4318
Phone
(267) 426-0311
E-mail
bassing[at]email.chop.edu
Website
http://www.med.upenn.edu/apps/faculty/index.php/g20000320/p5078061
Research Field
Molecular Biology
Award Year
2005

Research

Our focus is on the elucidation of molecular mechanisms that mediate the cellular response to DNA damage and direct genomic rearrangements in developing lymphocytes. One aspect of the lab centers on identifying mechanisms by which chromatin dynamics integrate Double Strand Break (DSB) repair with cellular proliferation and survival to prevent cancer. Another aspect of research in the lab centers on elucidating mechanisms by which chromatin dynamics regulate the tissue-, developmental stage-, and allele-specific rearrangement of antigen receptor loci.