Thomas F. Schilling, Ph.D.

Title
Professor
Department
Department of Developmental & Cell Biology
Institution
University of California, Irvine
Address
4109 Natural Sciences II
City, State, Zip
Irvine, CA 92697-2300
Phone
(949) 824-2479
E-mail
tschilli[at]uci.edu
Website
http://www.faculty.uci.edu/profile.cfm?faculty_id=4557
Research Field
Genetics
Award Year
2001

Research

Our laboratory uses genetics and molecular biology to study pattern formation in the early zebrafish embryo. The rapid development and simple anatomy of this teleost embryo, together with recently developed techniques for reverse genetics and a nearly complete genome sequence, make zebrafish a powerful molecular genetic system for studying the mechanisms of development. We focus on two areas: (i) neural crest specification and formation of the skeleton in the early embryo and (ii) long-range signals, morphogens, that pattern the anterior-posterior (A-P) axis of the nervous system. In both cases, we are interested in how gene functions translate into cell behaviours and the formation of tissues and organs.