Chinfei Chen, M.D., Ph.D.

Title
Associate Professor
Department
F.M. Kirby Neurobiology Center
Institution
Boston Children's Hospital, Harvard University
Address
300 Longwood Avenue
CLS 12250
City, State, Zip
Boston, MA 2115
Phone
(617) 919-2685
E-mail
Chinfei.Chen[at]childrens.harvard.edu
Website
http://dms.hms.harvard.edu/neuroscience/fac/Chenc.php
Research Field
Neuroscience
Award Year
2001

Research

The goal of Chinfei Chen’s research is to provide insight into neurological disorders that result from aberrant synaptic connections, such as some forms of epilepsy and mental retardation. To this end, she and her colleagues are working to understand synaptic mechanisms that underlie developmental synaptic remodeling and contribute to the processing of information in the immature and mature central nervous system. In one line of investigation, her lab focuses on how firing patterns of retinal ganglion cells are decoded into the output of the thalamocortical relay neurons. They are interested in understanding how specific retinal firing patterns and how ascending neurotransmitter systems from the brainstem alter the strength of the retinogeniculate synapse. Another area of her research examines the factors that are important in the formation and refinement of synaptic connections during development.