Yue Xiong, Ph.D.

Title
William R. Kenan Professor
Department
Department of Biochemistry and Biophysics
Institution
University of North Carolina at Chapel Hill
Address
22-012 Lineberger Cancer Center
Campus Box 7295
City, State, Zip
Chapel Hill, NC 27599-3280
Phone
(919) 962-2142
E-mail
yxiong[at]email.unc.edu
Website
http://cancer.med.unc.edu/xionglab/public_html/
Research Field
Molecular Biology
Award Year
1995

Research

The major goal of the laboratory is to combine genetics, cellular, biochemical and proteomic approaches to determine the mechanisms controlling the cell cycle in normal human cells, in both stem and somatic cells, and how this control is altered during tumorigenesis. Three major areas of our current research are: 1) Cancer and stem cell cycle control by CDK inhibitors 2) Control of p53 ubiquitylation and 3) Cullin-Ring family E3 ubiquitin ligases.