Marjorie A. Oettinger, Ph.D.

Title
Professor
Department
Molecular Biology
Institution
Massachusetts General Hospital, Harvard University
Address
Harvard Medical School/Kennedy School of Government
Richard B. Simches Research Building, 185 Cambridge St. - CPZN-7240
City, State, Zip
Boston, MA 02114
Phone
(617) 726-5967
E-mail
oettinger[at]molbio.mgh.harvard.edu
Website
http://molbio.mgh.harvard.edu/laboratories/oettinger
Research Field
Immunology
Award Year
1992

Research

The various projects in my laboratory are connected by one central theme: we seek to understand all facets of the V(D)J rearrangements that generate diversity within the vertebrate immune system. Specifically we are studying the enzymatic and regulatory machinery involved, the mechanism of the reaction, and the role of chromatin structure in the regulation of recombination events during lymphoid development. In addition, we are interested in how errors in this process lead to various human diseases.