Daniel D. Kalderon, Ph.D.

Title
Professor
Department
Department of Biological Sciences
Institution
Columbia University
Address
1212 Amsterdam Ave
1013 Fairchild Bldg
City, State, Zip
New York, NY 10027
Phone
(212) 854-6469
E-mail
ddk1[at]columbia.edu
Website
http://www.columbia.edu/cu/biology/faculty-data/daniel-kalderon/faculty.html
Research Field
Genetics
Award Year
1989

Research

Our general objectives are to understand how cell behaviors are regulated by communications between cells in development by using Drosophila molecular genetics supplemented by suitable biochemical and microscopy approaches. Our earlier investigations of the functions of Protein Kinase A (PKA) led us to study how a Hedgehog signal is transduced to alter cellular behavior, and this in turn led us to investigate how somatic stem cells in the Drosophila ovary are regulated by Hedgehog and other factors. Our two main focuses are 1) Mechanism of Hedgehog Signal Transduction 2) Regulation of somatic stem cells in the Drosophila ovary.